# name
Extracellular vesicles in parasitic diseases

# metadata.dc.description.abstract[].value
Parasitic diseases affect billions of people and are considered
                a major public health issue. Close to 400 species are estimated
                to parasitize humans, of which around 90 are responsible for
                great clinical burden and mortality rates. Unfortunately, they
                are largely neglected as they are mainly endemic to poor
                regions. Of relevance to this review, there is accumulating
                evidence of the release of extracellular vesicles (EVs) in
                parasitic diseases, acting both in parasite-parasite
                inter-communication as well as in parasite-host interactions.
                EVs participate in the dissemination of the pathogen and play a
                role in the regulation of the host immune systems. Production of
                EVs from parasites or parasitized cells has been described for a
                number of parasitic infections. In this review, we provide the
                most relevant findings of the involvement of EVs in
                intercellular communication, modulation of immune responses,
                involvement in pathology, and their potential as new diagnostic
                tools and therapeutic agents in some of the major human
                parasitic pathogens.

# metadata.dc.relation.ispartof[].value
Journal of Extracellular Vesicles, 2014, núm. 3, p. 25040

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Extracellular vesicles in parasitic diseases