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Regional homogeneity, ALFF and fALFF in rs-fMRI in a Alzheimer’s disease rat model

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2023, Tutor: Raúl Tudela Fernández

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In this study, a Python algorithm was implemented for calculating ReHo, ALFF, and fALFF from rs-fMRI images using AFNI software for an Alzheimer’s disease rat model. The study included both genetically modified and wild-type rats, with subsets of each undergoing specific training. The effect of neighborhood size on ReHo calculation was studied, and the temporal evolution of the means for each process was analyzed. Comparisons between the different rat groups revealed greater differences in female rat groups compared to male groups

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Regional homogeneity, ALFF and fALFF in rs-fMRI in a Alzheimer’s disease rat model