# name
Incidental mosquitocidal effect of an ivermectin mass drug
                administration on Anopheles farauti conducted for scabies
                control in the Solomon Islands

# metadata.dc.description.abstract[].value
Background: The Solomon Islands is targeting elimination of
                malaria by 2030. The dominant vector is the predominantly
                exophagic, exophilic Anopheles farauti sensu strictu. This
                biting behaviour limits the efficacy of conventional vector
                control tools and highlights the need for new strategies. When
                administered to humans ivermectin has been shown to have a
                mosquitocidal effect. Mass drug administration (MDA) with
                ivermectin is an emerging strategy in the control of scabies. In
                this study we explored any incidental effect of ivermectin MDA
                conducted for scabies control on mosquitoes. Methods: MDA for
                scabies was conducted in three villages. We performed human
                landing catches and measured 5-day mortality amongst Anopheles
                mosquitoes caught before and after MDA. Cox regression was used
                to calculate hazard ratios (HR) for mortality between mosquitoes
                caught before and after MDA. Results: There was a significant
                increase in 5-day mortality in anopheline mosquitoes caught
                post-MDA which was highest on the day of MDA itself (HR 4.2 95%
                CI 1.8 to 10.1, p=0.001) and the following day (HR 4.4 95% CI
                1.8 to 10.8, p=0.002) compared to mosquitoes caught before MDA.
                Conclusions: This study shows a possible mosquitocidal effect of
                ivermectin MDA conducted for scabies control. Studies with a
                larger sample size with clinical as well as entomological
                outcomes should be conducted in this population.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1093/trstmh/trx025

# metadata.dc.relation.ispartof[].value
Transactions of the Royal Society of Tropical Medicine and
                Hygiene, 2017, vol. 111, num. 3, p. 97-101

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Incidental mosquitocidal effect of an ivermectin mass drug
                administration on Anopheles farauti conducted for scabies
                control in the Solomon Islands