# name
Insulin resistance compensation: not just a beta cell matter?

# metadata.dc.description.abstract[].value
The global epidemic of type 2 diabetes is largely secondary to insulin resistance induced by obesity and sedentary lifestyles. Most insulin-resistant subjects are able to increase b-cell secretion to meet the increased insulin demand and do not develop diabetes. However, when b-cell compensation fails, type 2 diabetes develops (1,2). Understanding the mechanisms of this compensatory response is of fundamental importance to elucidate the pathophysiology of type 2 diabetes and has implications for the treatment of the disease.

# metadata.dc.rights[].value
cc-by-nc-nd (c) American Diabetes Association, 2014

# metadata.dc.source[].value
Articles publicats en revistes (Ciències Clíniques)

# metadata.dc.title[].value
Insulin resistance compensation: not just a beta cell matter?