# name
Bike peptides: a ride through the membrane

# metadata.dc.description.abstract[].value
Several natural peptides have a biaryl or biaryl ether motif in their biologically active structures. A model bicyclic pentapeptide
containing a biaryl bridge has been synthesized by solid-phase peptide synthesis combining on-resin Suzuki and Miyaura
cross-coupling reactions. Its biological properties in terms of permeability, stability and cytotoxicity have been studied, demon-strating the positive contribution of the biaryl bridge, excellent membrane penetration and serum stability

# metadata.dc.rights[].value
(c) European Peptide Society and John Wiley & Sons, 2017

# metadata.dc.source[].value
Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

# metadata.dc.title[].value
Bike peptides: a ride through the membrane