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Can Economic Analysis Contribute to Disease Elimination and
                Eradication? A Systematic Review

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BACKGROUND: Infectious diseases elimination and eradication have
                become important areas of focus for global health and countries.
                Due to the substantial up-front investments required to
                eliminate and eradicate, and the overall shortage of resources
                for health, economic analysis can inform decision making on
                whether elimination/eradication makes economic sense and on the
                costs and benefits of alternative strategies. In order to draw
                lessons for current and future initiatives, we review the
                economic literature that has addressed questions related to the
                elimination and eradication of infectious diseases focusing on:
                why, how and for whom? METHODS: A systematic review was
                performed by searching economic literature (cost-benefit,
                cost-effectiveness and economic impact analyses) on
                elimination/eradication of infectious diseases published from
                1980 to 2013 from three large bibliographic databases: one
                general (SCOPUS), one bio-medical (MEDLINE/PUBMED) and one
                economic (IDEAS/REPEC). RESULTS: A total of 690 non-duplicate
                papers were identified from which only 43 met the inclusion
                criteria. In addition, only one paper focusing on equity issues,
                the "for whom?" question, was found. The literature relating to
                "why?" is the largest, much of it focusing on how much it would
                cost. A more limited literature estimates the benefits in terms
                of impact on economic growth with mixed results. The question of
                how to eradicate or eliminate was informed by an economic
                literature highlighting that there will be opportunities for
                individuals and countries to free-ride and that forms of
                incentives and/or disincentives will be needed. This requires
                government involvement at country level and global coordination.
                While there is little doubt that eliminating infectious diseases
                will eventually improve equity, it will only happen if active
                steps to promote equity are followed on the path to elimination
                and eradication. CONCLUSION: The largest part of the literature
                has focused on costs and economic benefits of
                elimination/eradication. To a lesser extent, challenges
                associated with achieving elimination/eradication and ensuring
                equity have also been explored. Although elimination and
                eradication are, for some diseases, good investments compared
                with control, countries' incentives to eliminate do not always
                align with the global good and the most efficient elimination
                strategies may not prioritize the poorest populations. For any
                infectious disease, policy-makers will need to consider
                realigning contrasting incentives between the individual
                countries and the global community and to assure that the
                process towards elimination/eradication considers equity.

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Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Can Economic Analysis Contribute to Disease Elimination and
                Eradication? A Systematic Review