# name
Human Translational Research in Psoriasis Using CLA+ T Cells

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Focusing on the study of human memory CLA+ T cells to understand psoriasis pathology constitutes an innovative approach to explore the pathological mechanism of this chronic cutaneous inflammatory disease. CLA+ T cells can be considered peripheral cell biomarkers in the study of T-cell mediated human skin diseases. During the last few years, new evidences have been found that link streptococcal infection with IL-17 response in psoriasis by studying the interaction between Streptococcus pyogenes with CLA+ T cells and autologous epidermal cells. S. pyogenes constitutes the best clinically characterized trigger of psoriasis and by exploring its effect on CLA+ T cells and epidermal cells in psoriasis may allow understanding psoriasis by using patient’s clinical samples ex vivo.

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cc by (c) Ruiz Romeu, Ester 1 et al., 2017

# metadata.dc.source[].value
Llibres / Capítols de llibre (Biologia Cel·lular, Fisiologia i Immunologia)

# metadata.dc.title[].value
Human Translational Research in Psoriasis Using CLA+ T Cells