# name
Circadian functioning and quality of life in substance use disorder patients with and without comorbid schizophrenia

# metadata.dc.description.abstract[].value
Sleep disturbances are strongly linked with mental diseases such as substance use disorder (SUD) or schizophrenia (SZ) which can have a detrimental impact on quality of life (QOL), especially when both disorders are comorbid (dual disorder). In absence of studies about both circadian characteristics and QOL in patients with SUD and comorbid SZ (SUD + SZ), we examined a sample of 155 male under treatment, 75 with SUD + SZ and 80 only with SUD. Circadian functioning was evaluated by chronotype, social jet-lag and sleep quality (using the Pittsburgh Sleep Quality Index, PSQI), while the QOL was obtained by the World Health Organization’s Quality of Life Questionnaire (WHOQOL)-BREF. SUD + SZ patients were more evening type than SUD, and this chronotype was linked to polydrug use in total sample and SUD + SZ group. We observed that the comorbidity did not lead to worse sleep quality in the SUD and SUD + SZ patients. QOL was poorer in SUD + SZ patients, who showed a negative association of Physical health, Psychological health and Social relationship with suicide at tempts and severity of SZ. Lastly, patients with worse QOL also reported poorer sleep quality suggesting that treatment could include circadian adjustments along with a focused approach to lifestyle improvement.

# metadata.dc.relation.ispartof[].value
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2023, vol. 120, 110623

# metadata.dc.rights[].value
cc by-nc-nd (c) Hashemzadeh, Iman et al., 2023

# metadata.dc.source[].value
Articles publicats en revistes (Psicologia Clínica i Psicobiologia)

# metadata.dc.title[].value
Circadian functioning and quality of life in substance use disorder patients with and without comorbid schizophrenia