# name
Point of care diagnostics for tuberculosis

# metadata.dc.description.abstract[].value
The goals of the End TB strategy, which aims to achieve a 90%
                reduction in tuberculosis (TB) incidence and a 95% reduction in
                TB mortality by 2035, will not be achieved without new tools to
                fight TB. These include improved point of care (POC) diagnostic
                tests that are meant to be delivered at the most decentralised
                levels of care where the patients make the initial contact with
                the health system, as well as within the community. These tests
                should be able to be performed on an easily accessible sample
                and provide results in a timely manner, allowing a quick
                treatment turnaround time of a few minutes or hours (in a single
                clinical encounter), hence avoiding patient loss-to-follow-up.
                There have been exciting developments in recent years, including
                the WHO endorsement of Xpert MTB/RIF, Xpert MTB/RIF Ultra,
                loop-mediated isothermal amplification (TB-LAMP) and lateral
                flow lipoarabinomannan (LAM). However, these tests have
                limitations that must be overcome before they can be optimally
                applied at the POC. Furthermore, worrying short- to medium-term
                gaps exist in the POC diagnostic test development pipeline.
                Thus, not only is better implementation of existing tools and
                algorithms needed, but new research is required to develop new
                POC tests that allow the TB community to truly make an impact
                and find the "missed TB cases".

# metadata.dc.relation.isformatof[].value
Versió postprint del document publicat a:
                http://dx.doi.org/10.1016/j.rppnen.2017.12.002

# metadata.dc.relation.ispartof[].value
Revista Portuguesa de Pneumologia - Pulmonology Journal, 2018

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Point of care diagnostics for tuberculosis