# name
Synthesis and prelimnary biological evaluation of 1,3,5-triazine amino acid derivatives to study their MAO inhibitors

# metadata.dc.description.abstract[].value
Three series of 4,6-dimethoxy-, 4,6-dipiperidino- and 4,6-dimorpholino-1,3,5-triazin-2-yl) amino acid derivatives were synthesized and characterized. A preliminary study for their monoamine oxidase inhibitory activity showed that compounds 7, 18, and 25 had MAO-A inhibition activity comparable to that of the standard clorgyline, with apparently more selective inhibitory activity toward MAO-A than MAO-B and no significant acute toxicity.

# metadata.dc.rights[].value
cc-by (c) Khattab, Sherine N. et al., 2015

# metadata.dc.source[].value
Articles publicats en revistes (Química Inorgànica i Orgànica)

# metadata.dc.title[].value
Synthesis and prelimnary biological evaluation of 1,3,5-triazine amino acid derivatives to study their MAO inhibitors