# name
Pertussis vaccination during pregnancy: Antibody persistence in
                infants

# metadata.dc.description.abstract[].value
Maternal pertussis vaccination is associated with higher levels
                of pertussis antibodies at birth. We assessed the persistence of
                pertussis antibodies until primary vaccination in infants whose
                mothers received Tdap (tetanus, diphtheria, acellular pertussis)
                vaccine during pregnancy. Infants were born at the Hospital
                Clinic of Barcelona (Spain) in November 2014. Anti-PT IgG was
                determined by ELISA at delivery, between the first and second
                month of life, and estimated at 2months of age. The study
                included 37 infants whose mothers received Tdap between 21 and
                38weeks of gestation. Infants presented a decline in GMC of
                anti-PT IgG between peripartum and follow-up levels, 52.7 (95%
                CI 34.7-80.2) versus 7.5 (95% CI 4.2-13.3) at 2months of age
                (p<0.001). The median half-life of maternal antibodies was
                47days. More than half (51.4%) the infants presented detectable
                anti-PT IgG before the start of primary infant vaccination.

# metadata.dc.relation.isformatof[].value
Versió postprint del document publicat a:
                http://dx.doi.org/10.1016/j.vaccine.2016.05.051

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Pertussis vaccination during pregnancy: Antibody persistence in
                infants