# metadata.dc.description.abstract[].value
The synthesis and aqueous self-assembly of a new class of amphiphilic aliphatic polyesters are presented. These AB block polyesters comprise polycaprolactone (hydrophobe) and an alternating polyester from succinic acid and an ether-substituted epoxide (hydrophile). They self-assemble into biodegradable polymersomes capable of entering cells. Their degradation products are bioactive, giving rise to differentiated cellular responses inducing stromal cell proliferation and macrophage apoptosis. Both effects emerge only when the copolymers enter cells as polymersomes and their magnitudes are size dependent.

# metadata.dc.relation.ispartof[].value
Angewandte Chemie-International Edition, 2019, vol. 58, num.14, p. 4581-4586

# metadata.dc.source[].value
Articles publicats en revistes (Física Aplicada)