# name
RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease

# metadata.dc.description.abstract[].value
We found an unanticipated recovery of several gliosis hallmarks and inflammasome key proteins upon neuronal RTP801 downregulation in the 5xFAD mice. Altogether our results suggest that RTP801 could be a potential future target for theranostic studies since it could be a biomarker of neuroinflammation and neurotoxicity severity of the disease and, at the same time, a promising therapeutic target in the treatment of AD.

# metadata.dc.relation.ispartof[].value
Cell Death and Disease, 2021, vol. 12, num.6

# metadata.dc.rights[].value
cc-by (c) Pérez Sisqués, Leticia et al., 2021

# metadata.dc.source[].value
Articles publicats en revistes (Biomedicina)

# metadata.dc.title[].value
RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease