# name
Naturally acquired antibody responses to more than 300
                Plasmodium vivax proteins in three geographic regions

# metadata.dc.description.abstract[].value
Plasmodium vivax remains an important cause of malaria in South
                America and the Asia-Pacific. Naturally acquired antibody
                responses against multiple P. vivax proteins have been described
                in numerous countries, however, direct comparison of these
                responses has been difficult with different methodologies
                employed. We measured antibody responses against 307 P. vivax
                proteins at the time of P. vivax infection, and at 2-3 later
                time-points in three countries. We observed that seropositivity
                rates at the time of infection were highest in Thailand,
                followed by Brazil then PNG, reflecting the level of antigenic
                input. The majority of sero-reactive antigens in all sites
                induced short-lived antibody responses with estimated half-lives
                of less than 6 months, although there was a trend towards
                longer-lived responses in PNG children. Despite these
                differences, IgG seropositivity rates, magnitude and longevity
                were highly and significantly rank-correlated between the
                different regions, suggesting such features are reflective of
                the individual protein.

# metadata.dc.relation.isformatof[].value
Reproducció del document publicat a:
                http://dx.doi.org/10.1371/journal.pntd.0005888

# metadata.dc.relation.ispartof[].value
PLoS Neglected Tropical Diseases, 2017, vol. 11, num. 9, p.
                e0005888

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Naturally acquired antibody responses to more than 300
                Plasmodium vivax proteins in three geographic regions