# name
Prioritizing surveillance activities for certification of yaws
                eradication based on a review and model of historical case
                reporting

# metadata.dc.description.abstract[].value
BACKGROUNDt: The World Health Organization
                (WHO) has targeted yaws for global eradication. Eradication
                requires certification that all countries are yaws-free. While
                only 14 Member States currently report cases to WHO, many more
                are known to have a history of yaws and some of them may have
                ongoing transmission. We reviewed the literature and developed a
                model of case reports to identify countries in which passive
                surveillance is likely to find and report cases if transmission
                is still occurring, with the goal of reducing the number of
                countries in which more costly active surveillance will be
                required. METHODSt: We reviewed published and
                unpublished documents to extract data on the number of yaws
                cases reported to WHO or appearing in other literature in any
                year between 1945 and 2015. We classified countries as: a)
                having interrupted transmission; b) being currently endemic; c)
                being previously endemic (current status unknown); or d) having
                no history of yaws. We constructed a panel dataset for the years
                1945-2015 and ran a regression model to identify factors
                associated with some countries not reporting cases during
                periods when there was ongoing (and documented) transmission.
                For previously endemic countries whose current status is
                unknown, we then estimated the probability that countries would
                have reported cases if there had in fact been transmission in
                the last three years (2013-2015)." - Label: RESULTS content:
                Yaws has been reported in 103 of the 237 countries and areas
                considered. 14 Member States and 1 territory (Wallis and Futuna
                Islands) are currently endemic. 2 countries are believed to have
                interrupted transmission. 86 countries and areas are previously
                endemic (current status unknown). Reported cases peaked in the
                1950s, with 55 countries reporting at least one case in 1950 and
                a total of 2.35 million cases reported in 1954. Our regression
                model suggests that case reporting during periods of ongoing
                transmission is positively associated with socioeconomic
                development and, in the short-term, negatively associated with
                independence. We estimated that for 66 out of the 86 previously
                endemic countries whose current status is unknown, the
                probability of reporting cases in the absence of active
                surveillance is less than 50%. DISCUSSION:
                Countries with a history of yaws need to be prioritized so that
                international resources for global yaws eradication may be
                deployed efficiently. Heretofore, the focus has been on mass
                treatment in countries currently reporting cases. It is also
                important to undertake surveillance in the 86 previously endemic
                countries for which the current status is unknown. Within this
                large and diverse group, we have identified a group of 20
                countries with more than a 50% probability of reporting cases in
                the absence of active surveillance. For the other 66 countries,
                international support for active surveillance will likely be
                required.

# metadata.dc.relation.ispartof[].value
PLoS Neglected Tropical Diseases, 2018, vol. 12, num. 12, p. e0006953

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Prioritizing surveillance activities for certification of yaws
                eradication based on a review and model of historical case
                reporting