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Streptococcus pneumoniae carriage among healthy and sick pediatric patients before the generalized implementation of the 13-valent pneumococcal vaccine in Morocco from 2010 to 2011

# metadata.dc.description.abstract[].value
Nasopharyngeal carriage studies provide insights into the local               prevalence of circulating pneumococcal serotypes. These data are
                critical to vaccination monitoring, as they allow for the
                prediction and assessment of impact. Very little data are
                available on the carriage of pneumococcal serotypes in Morocco.
                Here, we describe the prevalence of Streptococcus pneumoniae
                carriage and serotype distribution among 697 pediatric patients
                with ages ranging from 2 to 59 months who were admitted to a
                Moroccan hospital with severe pneumonia, as well as 195 healthy
                infants and young children who were recruited at a vaccination
                clinic. Carriage rates were 40.5% (79/195) for healthy children
                and 22.8% (159/697) for sick children. The most commonly
                observed circulating serotypes included 6A, 6B and 19F, all of
                which are included in the current 13-valent anti-pneumococcal
                conjugate vaccine that was recently introduced in Morocco.
                Monitoring of circulating serotypes remains necessary after
                vaccine introduction to assess whether serotype replacement is
                occurring.

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Versió postprint del document publicat a:
                http://dx.doi.org/10.1016/j.jiph.2016.02.012

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Journal of Infection and Public Health, 2016

# metadata.dc.source[].value
Articles publicats en revistes (ISGlobal)

# metadata.dc.title[].value
Streptococcus pneumoniae carriage among healthy and sick pediatric patients before the generalized implementation of the 13-valent pneumococcal vaccine in Morocco from 2010 to 2011