# name
Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis

# metadata.dc.description.abstract[].value
Emotion dysregulation (ED) is characterized by rigid and frequent use of maladaptive emotion regulation (ER) strategies. Conceptualized as a transdiagnostic feature, ED may occur in both clinical and non-clinical populations, including people diagnosed with bipolar disorder (BD) and their first-degree relatives (FDRs), though expected to manifest with differential clinical features. To this end, we conducted a systematic review and meta-analysis of the literature comparing people with BD to healthy controls (HCs) or FDRs, from inception up to November 25, 2021, across major databases. Random-effects meta-analyses considered twenty-eight studies assessing ER/ED with a validated scale. Patients with BD differed from HCs in adopting more maladaptive ER strategies, such as rumination, risk-taking behaviors, negative focus, and less adaptive ones. Unaffected FDRs differed from people with BD, yet to a lower extent, suggesting that ED may span a continuum. ED in BD should be widely explored to better understand its course and management, with specific interventions aimed at reducing its burden on both high-risk and full-threshold populations.

# metadata.dc.relation.ispartof[].value
Neuroscience and Biobehavioral Reviews, 2022, vol. 142, p. 104914

# metadata.dc.rights[].value
cc-by-nc-nd (c) De Prisco, Michele et al., 2022

# metadata.dc.source[].value
Articles publicats en revistes (Medicina)

# metadata.dc.title[].value
Defining clinical characteristics of emotion dysregulation in bipolar disorder: A systematic review and meta-analysis