# name
Preparation of benzolactams by Pd(II)-catalyzed carbonylation of N-unprotected arylethylamines

# metadata.dc.description.abstract[].value
An unprecedented NH2-directed Pd(II)-catalytic carbonylation of quaternary aromatic α -amino esters to yield 6-membered 10 benzolactams has been developed. The reaction shows a strong bias to 6-membered lactams over 5-membered ones. The steric hindrance around the amino group seems to be pivotal for the success of the process.

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Articles publicats en revistes (Química Inorgànica i Orgànica)

# metadata.dc.title[].value
Preparation of benzolactams by Pd(II)-catalyzed carbonylation of N-unprotected arylethylamines