# name
Indole Content Profiling During Biological Ageing of Cava Sparkling Wine

# metadata.dc.description.abstract[].value
Indoles are bioactive components found in wine products and are associated
with yeast activity. Cava, a Spanish sparkling wine, is characterized by aging in contact with lees, making it a potential matrix for indoles. Therefore, the aim of this study was to determine the indole content in Cava produced at an industrial scale. Nine indoles were analysed by Ultra High-Performance Liquid Chromatography—Tandem Mass Spectrometry in Cava samples with different ageing times (n = 74). Significant amounts of tryptophan (2.3–1680.4 µg/L), tryptophan ethyl ester (0.1–5.2 µg/L), 5-methoxytryptophol (0.3–29.2 µg/L) and n-acetyl serotonin (0.3–2.3 µg/L) were determined. Tryptophan and tryptophan ethyl ester were positively correlated and decreased with ageing time. In fact, a
concentration of less than 0.56 µg of the latter indole can become a marker of the most aged Cavas. The ageing time in contact with lees seems to play a key role affecting the indole content, since base wines show high amount of tryptophan and tryptophan ethyl ester while aged sparkling wines have values around the lower 95% confidence limit. Notably, the identification of tryptophan ethyl ester as a potential marker for aging in Cava suggests a new avenue for further research and quality assessment in its production

# metadata.dc.rights[].value
cc-by (c) Abarca-Rivas, Clara et al., 2025

# metadata.dc.source[].value
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

# metadata.dc.subject.classification[].value
Cromatografia de líquids d'alta resolució

# metadata.dc.title[].value
Indole Content Profiling During Biological Ageing of Cava Sparkling Wine