Companys Alemany, JúliaCozar, MónicaGrinberg Vaisman, Daniel RaúlVilageliu i Arqués, LluïsaCodony Gisbert, SandraVázquez Cruz, SantiagoPallàs i Llibería, Mercè, 1964-Griñán Ferré, Christian2020-09-162020-09-162020-09https://hdl.handle.net/2445/170656Niemann-Pick type C (NPC) disease is a childhood autosomal recessive inherited rare neurodegenerative disease characterized by accumulation of cholesterol and glycosphingolipids and where the autophagy-lysosome system and inflammatory processes are implicated in the pathogenesis of the disease. We follow a novel approach to deal with NPC disease, by modulating key features of the disease such as inflammation and autophagy, through inhibition of soluble epoxide hydrolase (sEH).1 p.application/pdfengcc by-nc-nd (c) Companys Alemany, Júlia et al., 2020http://creativecommons.org/licenses/by-nc-nd/3.0/es/Malalties de Niemann-PickTrastorns del metabolismeCognicióNiemann-Pick diseasesDisorders of metabolismCognitioninfo:eu-repo/semantics/conferenceObjectinfo:eu-repo/semantics/openAccess