Moreso, FrancescAntonio Pons Miñano, JoséSánchez Fructuoso, AnaJacas, CarlosAlegret, MontserratFerrer, MontserratColmenero, JordiAndrés Belmonte, AmadoLópez Jiménez, VerónicaPascual, SoniaMazuecos Blanca, AuxiliadoraVentura Galiano, Ana PazCachero, AlbaRivero, AntonioCrespo, MartaCuadrado, AntonioCaballero Marcos, ArantxaGonzalez Diéguez, Maria LuisaAlmohalla Alvarez, CarolinaMaruri Kareaga, NaroaAlamo Martinez, Jose M.Pagano, GiuliaNuño Santana, EnriquetaTorres, Irina B.Pérez Flores, IsabelAlonso Titos, JuanaRodríguez Soler, MaríaMartinez Alarcón, LauraGarcía Álvarez, Teresa MaríaBeneyto Castelló, IsabelGonzalez Vilatarsana, EmmaMiras, FrancescGómez Bravo, Miguel Ángel2025-07-012025-07-012025-01-281600-6143https://hdl.handle.net/2445/221932We created and validated the Neuro-Score, a specific scale to detect and monitor cognitive impairment, including mild stages, in kidney or liver transplant recipients. A qualitative study was conducted to define a preliminary set of 62 items. Item reduction was performed using exploratory factor analysis. Confirmatory factor analysis assessed the adequacy of the factorial solution. The total scores of the Neuro-Score and mini-mental state examination were compared. Responsiveness to change was evaluated from visit 1 (baseline) to 2A (18 months later) and temporal stability from visit 2A to 2B (1-2 weeks later). Factor analysis showed 11 factors with an eigenvalue of >1. Confirmatory factor analysis yielded a logical solution with 1 factor and 11 items that explained 27.9% of the variance. The final model showed satisfactory internal consistency (Cronbach alpha- 0.82). A weak negative correlation was found between Neuro-Score and mini-mental state examination total scores (Pearson r--0.12; P-.0095). The Neuro-Score responsiveness to change was demonstrated (P-.022). No significant differences in the total score were observed between visits 2A and 2B, supporting the Neuro-Score temporal stability. The Neuro-Score scale is a simple, reliable, self-administered, easy-to-interpret, and consistent 11-item scale to detect and monitor cognitive impairment in kidney and liver transplant recipients.11 p.application/pdfengcc by-nc-nd (c) Moreso, Francesc et al., 2025http://creativecommons.org/licenses/by-nc-nd/3.0/es/Trastorns de la cognicióTrasplantament renalTrasplantament hepàticHepatic transplantationCognition disordersKidney transplantationinfo:eu-repo/semantics/article2025-06-26info:eu-repo/semantics/openAccess39880125