OTAC: Optimization of Antibiotic Therapy in Critically ill Patients. Using beta-lactam antibiotics by continuous infusion

Esteve Pitarch, ErikaPadullés Zamora, AriadnaMaisterra-Santos, KristelColom Codina, HelenaCobo Sacristán, Sara2021-03-182021-03-1820190210-6329https://hdl.handle.net/2445/175294Objective: To determine the percentage of patients given standard doses of piperacillin/tazobactam or meropenem by continuous infusion who achieved the target pharmacokinetic/pharmacodynamic (PK/PD) index, which was defined as free concentrations four times more than the minimum inhibitory KEYWORDS Beta-lactams; Critical care; Pharmacokinetics; Drug monitoring; Piperacillin; Meropenem.7 p.application/pdfengcc by-nc-sa (c) Sociedad Española de Farmacia Hospitalaria, 2019http://creativecommons.org/licenses/by-nc-sa/3.0/es/Antibiòtics betalactàmicsMedicina intensivaFarmacocinèticaBeta lactam antibioticsCritical care medicinePharmacokineticsOTAC: Optimization of Antibiotic Therapy in Critically ill Patients. Using beta-lactam antibiotics by continuous infusioninfo:eu-repo/semantics/article6983942021-03-18info:eu-repo/semantics/openAccess