Fernández Aranda, FernandoAgüera, ZaidaFernández-García, Jose C.Garrido-Sanchez, LourdesTinahones, Francisco J.Giner Bartolomé, CristinaBaños Rivera, Rosa MaríaBotella Arbona, CristinaCebolla, Ausiasde la Torre, RafaelFernández-Real Lemos, José ManuelOrtega González, Fco. JavierFrühbeck, GemaGómez Ambrosi, JavierGranero, RoserIslam, Mohammed AnisulJiménez-Murcia, SusanaTárrega, SaloméMenchón Magriñá, José ManuelFagundo, Ana BeatrizSancho, CarolinaEstivill, Xavier, 1955-Treasure, JanetCasanueva, Felipe F.2023-05-162023-05-162016-02-010013-7227https://hdl.handle.net/2445/198072(1) The objective of this study is to analyze differences in smell-taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through 'Sniffin' Sticks' and 'Taste Strips,' respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.12 p.application/pdfeng(c) Association for the Study of Internal Secretions, 2016Anorèxia nerviosaPes corporalColecistocininaObesitatAnorexia nervosaBody weightCholecystokininObesityinfo:eu-repo/semantics/article6693632023-05-16info:eu-repo/semantics/openAccess26198367