Hernández García, MaríaSolito, ClaudiaPavón Ortiz, AlbaArguedas Casamayor, NoeliaMelé Casas, MariaPons Tomàs, GemmaFernández de Sevilla Estrach, MarionaPino Ramírez, Rosa MaríaLaunes Montaña, CristianGuitart, CarminaGirona Alarcón, MònicaJordán García, IolandaGarcía García, Juan José2025-05-222025-05-222023-10-192227-9067https://hdl.handle.net/2445/221176SARS-CoV-2 pneumonia in children has a lower incidence and severity compared to adults. Risk factors are adolescence and comorbidities. Our aims were to describe the characteristics of children admitted with SARS-CoV-2 pneumonia, identify risk factors associated with severity and compare the cases according to the variant of SARS-CoV-2. This was a descriptive and retrospective study, including patients aged 0-18 years hospitalized in a tertiary-care hospital between l March 2020 and l March 2022. Epidemiological, clinical, diagnostic and therapeutic data were analyzed. Forty-four patients were admitted; twenty-six (59%) were male and twenty-seven (61 %) were older than 12 years. Thirty-six (82%) had comorbidities, the most frequent of which were obesity and asthma. Seven (15.9%) patients required high-flow oxygen, eleven (25%) non-invasive ventilation and four (9.1 %) conventional mechanical ventilation. In critically ill patients, higher levels of anemia, lymphopenia, procalcitonin, lactate dehydrogenase (LDH) and hypoalbuminemia and lower levels of HDL-cholesterol were detected (all p < 0.05). Prematurity (p = 0.022) was associated with intensive care unit adrnission. Patients were younger during the Omicron wave (p < O.Ol); no variant was associated with greater severity. In conclusion, pediatric patients with a history of prematurity or with anemia, lymphopenia, elevated procalcitonin, elevated LDH levels, hypoalbuminemia and low HDL-cholesterol levels may require admission and present more severe forms. Apart from age, no notable differences between SARS-CoV-2 variant periods were found.15 p.application/pdfengcc-by (c) Hernández-García, M et al., 2023http://creativecommons.org/licenses/by/4.0/Factors de risc en les malaltiesPneumòniaSARS-CoV-2COVID-19PediatriaRisk factors in diseasesPneumoniaSARS-CoV-2COVID-19Pediatricsinfo:eu-repo/semantics/article7466622025-05-22info:eu-repo/semantics/openAccess37892366