Larriba, SaraSánchez Herrero, José FranciscoPluvinet Ortega, RaquelLópez Rodrigo, OlgaBassas, LluísSumoy, Lauro2023-07-192024-05-272023-05-272047-2927https://hdl.handle.net/2445/200868Background: Non-invasive molecular biomarkers for classifying azoospermia by origin into either obstructive or non-obstructive/secretory azoospermia, as well as for inferring the spermatogenic reserve of the testis of non-obstructive/secretory azoospermia patients, are of great interest for testicular sperm retrieval outcome prediction for assisted reproduction. Prior analyses of semen small non-coding RNA expression in azoospermia have focused on microRNAs, but there has been a lack of attention on other regulatory small RNA species. In this regard, studying more in-depth expression changes of small non-coding RNA subtypes in small extracellular vesicles from semen of azoospermic individuals could be useful to select additional non-invasive biomarkers with diagnostic/prognostic purposes.58 p.application/pdfeng(c) Wiley, 2023Esterilitat masculinaInvestigació mèdicaMale sterilityMedicine researchSeminal extracellular vesicle sncRNA sequencing reveals altered miRNA/isomiR profiles as sperm retrieval biomarkers for azoospermiainfo:eu-repo/semantics/article2023-06-15info:eu-repo/semantics/openAccess37245055