Mice with Pulmonary Tuberculosis Treated with Mycobacterium vaccae Develop Strikingly Enhanced Recall Gamma Interferon Responses to M. vaccae Cell Wall Skeleton

Rodríguez Güell, ElisabethAgustí, GemmaCorominas Sánchez, MercèCardona, Pere-JoanLuquin, MarinaJulián, Esther2018-11-232018-11-232008-05https://hdl.handle.net/2445/126418Whole heat-killed Mycobacterium vaccae is used as an immunotherapeutic agent in tuberculosis (TB), but the compound(s) that triggers its immunostimulatory ability is not known. Here, we show that among different subcellular fractions, the cell wall skeleton induced a prominent expression of gamma interferon in splenocytes from both non-TB and TB M. vaccae-treated mice.4 p.application/pdfeng(c) American Society for Microbiology, 2008Mycobacterium tuberculosisRatolins (Animals de laboratori)Mice (Laboratory animals)Mice with Pulmonary Tuberculosis Treated with Mycobacterium vaccae Develop Strikingly Enhanced Recall Gamma Interferon Responses to M. vaccae Cell Wall Skeletoninfo:eu-repo/semantics/article2018-07-25info:eu-repo/semantics/openAccess18337379