Sánchez-Moreno, JoséBonnín Roig, Caterina del MarGonzález-Pinto, AnaAmann, Benedikt L.Solé Cabezuelo, BrisaBalanzá-Martínez, VicentArango, CelsoJiménez Martínez, EsterTabarés-Seisdedos, RafaelGarcía-Portilla González, María Paz, 1962-Ibáñez, ÁngelaCrespo, J. M. (José Manuel)Ayuso Mateos, José LuisVieta i Pascual, Eduard, 1963-Martínez-Arán, Anabel, 1971-Torrent Font, CarlaCIBERSAM Functional Remediation Group2026-02-122026-02-122017-040924-977Xhttps://hdl.handle.net/2445/226830We analyzed the efficacy of functional remediation, in a sample of patients with bipolar disorder who presented with subsyndromal symptoms. From a total sample of 239 patients with bipolar I and II disorder, according to DSM-IV-TR diagnostic criteria, entering a randomized clinical trial, those patients who presented with subsyndromal symptoms were selected based on a method already described by Berk and colleagues was applied. It consists of using the Clinical Global Impression-Bipolar version (CGI-BP) to establish the scores of the Hamilton Depression Rating Scale (HAM-D) and of the Young Mania Rating Scale (YMRS) that correspond with 1 in the CGI-BP. Functional outcome and mood symptoms were assessed at 6 and at 12-month follow-up. A total of 99 patients were selected for this post-hoc analysis, allocated as follows: functional remediation (n=33); psychoeducation (n=37) and treatment as usual (TAU,n=29). The repeated-measures analyses at 12-month follow-up revealed a significant group x time interaction in favour of the patients who received functional remediation when compared to psychoeducation and TAU (F=2.93; p=0.02) at improving psychosocial functioning. Finally, mood symptoms did not significantly change in any of the three groups at any time of follow-up, as shown by the non-significant group x time interaction effect in HAM-D scores (F=1.57; p=0.18) and YMRS scores (F=1.51; p=0.20). Bipolar patients with subsyndromal symptoms improve their functional outcome when exposed to functional remediation regardless of the persistence of mood symptomatology.55 p.application/pdfengcc-by-nc-nd (c) Elsevier B.V., 2017http://creativecommons.org/licenses/by-nc-nd/4.0/Trastorn bipolarIntervenció psicològicaManic-depressive illnessPsychological interventioninfo:eu-repo/semantics/article6670992026-02-12info:eu-repo/semantics/openAccess28126401