Xu, LimeiBuldyrev, V. S. (Vladimir Sergeevich)Stanley, H. Eugene (Harry Eugene), 1941-Franzese, Giancarlo2019-05-222019-05-222012-08-270031-9007https://hdl.handle.net/2445/133725Several scenarios exist for the protein crystallization and aggregation in solutions near a metastable fluid-fluid phase separation below the solubility line. Based on computations, it was proposed that the fluid-fluid critical point enhances the crystallization rate by many orders of magnitude, while, based on experiments, it was proposed that the fluid-fluid spinodal controls the crystallization rate. Using molecular dynamic simulations for an isotropic model with sticky interaction, we show that neither of these scenarios adequately describes the crystallization mechanism near a metastable fluid-fluid phase separation. We find that the emergence of the high-density fluid inside the spinodal drastically enhances the crystal nucleation in the subcritical region following Ostwald's rule of stages.5 p.application/pdfeng(c) American Physical Society, 2012Física de partículesExperimentsParticle physicsExperimentsinfo:eu-repo/semantics/article6181582019-05-22info:eu-repo/semantics/openAccess