Ferreira Monteiro, ElianaFernández Becerra, CarmenSilva Araujo, Maisa daRezende Messias, MariluceShozo Ozaki, LuisRibeiro de Castro Duarte, Ana MariaGalvao Bueno, MarinaCatao Dias, Jose LuizRomeiro Fernandes Chagas, CarolinaSilva Mathias, Bruno daGomes dos Santos, MayraSantos, Stéfanie VanessaMoreira Holcman, MarciaSouza, Julio Cesar de Jr.Kirchgatter, Karin2022-02-072022-02-0720202076-0817https://hdl.handle.net/2445/182968Plasmodium - Plasmodium brasilianum - P. malariae - P. malariae - P. falciparum - P. vivax - Plasmodium content: - "Non-human primates (NHPs) have been shown to be infected by parasites of the genus " - ", the etiological agent of malaria in humans, creating potential risks of zoonotic transmission. " - ", a parasite species similar to " - " of humans, have been described in NHPs from Central and South America, including Brazil. The merozoite surface protein 1 (MSP1), besides being a malaria vaccine candidate, is highly immunogenic. Due to such properties, we tested this protein for the diagnosis of parasite infection. We used recombinant proteins of " - " MSP1, as well as of " - " and " - ", for the detection of antibodies anti-MSP1 of these parasite species, in the sera of NHPs collected in different regions of Brazil. About 40% of the NHP sera were confirmed as reactive to the proteins of one or more parasite species. A relatively higher number of reactive sera was found in animals from the Atlantic Forest than those from the Amazon region, possibly reflecting the former more intense parasite circulation among NHPs due to their proximity to humans at a higher populational density. The presence of " - " positive NHPs in the surveyed areas, being therefore potential parasite reservoirs, needs to be considered in any malaria surveillance program."11 p.application/pdfengcc by (c) Ferreira Monteiro, Eliana et al, 2020http://creativecommons.org/licenses/by/3.0/es/MalàriaImmunitatMalariaImmunityinfo:eu-repo/semantics/article2022-02-04info:eu-repo/semantics/openAccess