Medina Bueno, Gonzalo ArturoFernández Montolí, Ma. EulaliaHeydari, FatimaPonce i Sebastià, JordiTous, SaraPeñafiel, Judith2024-10-182024-10-182024-07-312075-1729https://hdl.handle.net/2445/215881The objective of this study was to evaluate the relationship between the excision type and the persistence/recurrence of CIN2-3. A total of 227 women with CIN2-3 who were treated with LLETZ were evaluated. The types of excision according to the IFCPC 2011, volume, cone dimensions, margins of resection, post-cone high-risk human papillomavirus (HR-HPV) status, and viral load were studied. The time to recurrence was assessed using Kaplan-Meier curves. Persistent/recurrent CIN2-3 was found in 12 cases (5.2%). Type 1 excision was performed in 107 patients, with 7 recurrences (6.5%); type 2 excision in 74 patients, with 4 recurrences (5.4%); and type 3 excision in 46 patients, with 1 recurrence (2.1%). The percentage of clear margins in type 1 excisions was 44.9%, that in type 2 excisions was 59.5%, and that in type 3 excisions was 69.6% (<em>p</em> = 0.008). Type 1 excision was associated with 28.5% post-LLETZ HR-HPV positivity, that in type 2 reached 20.6%, and that in type 3 reached 11.4%; this difference was non-significant (<em>p</em> = 0.24). (4) Conclusions: Type 3 excision was associated with a larger proportion of clear margins and lower post-cone HR-HPV positivity, with a lower incidence of the persistence/recurrence of CIN2-3.13 p.application/pdfengcc-by (c) Medina Bueno, G.A. et al., 2024http://creativecommons.org/licenses/by/4.0/Cèl·lules epitelialsColl uteríPapil·lomavirusEpithelial cellsCervix uteriPapillomavirusesinfo:eu-repo/semantics/article7501412024-10-18info:eu-repo/semantics/openAccess