Synthesis of Alkaloids and Compounds Containing the 3,4-Benzomorphan Scaffold

Rodríguez, Laura G.Bonjoch i Sesé, JosepBradshaw, Ben2025-04-292025-04-292023-10-231434-193Xhttps://hdl.handle.net/2445/220699Several natural products, bearing an embedded hexahydro-2,6-methano-1-benzazocine framework (3,4-benzomorphan) – a heterocyclic regioisomer of the 6,7-benzomorphan substructure found in morphine alkaloids, have therapeutic potential for a variety of diseases. Biogenesis, biosynthetic approaches, and total syntheses of alkaloids or synthetic azapolycyclic compounds featuring the aforementioned azatricyclic ring system (i. e., a 3,4-benzomorphan scaffold) are reviewed.26 p.application/pdfengcc-by-nc-nd (c) Rodríguez et al., 2023http://creativecommons.org/licenses/by-nc-nd/3.0/es/AlcaloidesSíntesi orgànicaCiclització (Química)AlkaloidsOrganic synthesisRing formation (Chemistry)Synthesis of Alkaloids and Compounds Containing the 3,4-Benzomorphan Scaffoldinfo:eu-repo/semantics/article7454402025-04-29info:eu-repo/semantics/openAccess