Ghirardi, ElenaGriera Farres, RosaPiccichè, MiriamMolins i Grau, EliesFernández Cadenas, IsraelBosch Cartes, JoanAmat Tusón, Mercedes2017-03-072017-11-182016-11-181523-7060https://hdl.handle.net/2445/108046Cyclocondensation of (R)-phenylglycinol with stereoisomeric mixtures (racemates, cis/trans) of 3-substituted 2- oxocyclohexaneacetates stereoselectively afforded tricyclic oxazoloindolone lactams, from which straightforward procedures for the stereocontrolled formation of enantiopure 7-substituted octahydroindoles with a variety of stereochemical patterns have been developed. The methodology has been successfully applied to the synthesis of (+)-α-lycorane.4 p.application/pdfeng(c) American Chemical Society , 2016LactamesSíntesi asimètricaLactamsAsymmetric synthesisinfo:eu-repo/semantics/article6649922017-03-07info:eu-repo/semantics/openAccess27797535