Piperaquine Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers of Papua New Guinea after Administration of Three-Monthly Doses of Dihydroartemisinin

Millat Martínez, PereSalman, SamMoore, Brioni R.Baró Sastre, BàrbaraPage-Sharp, MadhuBatty, Kevin T.Robinson, Leanne J.Pomat, WilliamKarunajeewa, HarinLaman, MosesManning, LaurensMitjà Villar, OriolBassat Orellana, Quique2023-09-212023-09-212022-07-061098-6596https://hdl.handle.net/2445/202127Mass drug administration (MDA) with monthly dihydroartemisinin-piperaquine (DHA-PQP) appears useful in malaria control and elimination strategies. Determining the relationship between consecutive piperaquine phosphate (PQP) exposure and its impact on QT interval prolongation is a key safety consideration for MDA campaigns.25 p.application/pdfeng(c) American Society for Microbiology, 2022MalàriaFarmacocinèticaPapua Nova GuineaMalariaPharmacokineticsPapua New GuineaPiperaquine Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers of Papua New Guinea after Administration of Three-Monthly Doses of Dihydroartemisinin–Piperaquineinfo:eu-repo/semantics/article2023-09-21info:eu-repo/semantics/openAccess969322435862743