Prieur, VanessaPujol Dilmé, M. DolorsGuillaumet, Gérald2016-03-212016-09-302015-091434-193Xhttps://hdl.handle.net/2445/96646New pyrrolo[2,3-d]pyrimidines that have aryl groups at the 2-, 4-, and 6-positions were prepared by the arylation reaction of 4-chloro-7-methyl-2-(methylthio)-6-phenylpyrrolo[2,3-d]pyrimidine (6) and the corresponding arylboronic acid under Suzuki-Miyaura conditions followed by a second arylation under Liebeskind-Srogl cross-coupling conditions. A parallel study that began with the C-2 chemoselective arylation of 6 under Liebeskind-Srogl conditions followed by a Suzuki-Miyaura coupling at C-4 was carried out, and the results of each route were compared. All of the tranformations were performed under microwave irradiation.10 p.application/pdfeng(c) Wiley-VCH, 2015Compostos heterocíclicsNitrogenQuímica orgànicaReaccions químiquesHeterocyclic compoundsNitrogenOrganic chemistryChemical reactionsinfo:eu-repo/semantics/article6559652016-03-21info:eu-repo/semantics/openAccess