Paoluzzi, MatteoAngelani, LucaGosti, GiorgioMarchetti, M. CristinaPagonabarraga Mora, IgnacioRuocco, Giancarlo2022-04-062022-04-062021-06-012470-0045https://hdl.handle.net/2445/184778Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends to align the cell crawling direction with cell elongation in a biological tissue model. We find that the alignment interaction promotes nematic patterns in the fluid phase that eventually undergo a nonequilibrium phase transition into a quasihexagonal solid. Meanwhile, highly asymmetric cells do not undergo the liquid-to-solid transition for any value of the alignment coupling. In this regime, the dynamics of cell centers and shape fluctuation show features typical of glassy systems.application/pdfeng(c) American Physical Society, 2021Teixits (Histologia)Migració cel·lularTissuesCell migrationinfo:eu-repo/semantics/article7197582022-04-06info:eu-repo/semantics/openAccess