García Segura, PolMalagelada Grau, Cristina2025-04-282025-04-282023-01-201742-464Xhttps://hdl.handle.net/2445/220672The non-canonical functions of the transcription factor STAT3 have been poorly studied in comparison to its canonical mechanisms of gene expression activation. Here, Köhler et al. put the spotlight on a novel unconventional repressing mechanism of STAT3 over the REDD1 gene, named DDIT4. These findings are crucial to expand the knowledge of the stress-induced short-lived REDD1 protein that inactivates mTOR and the consequences of this fine-tuned regulation in the context of pathological conditions such as cancer or neurodegenerative diseases.5 p.application/pdfengcc by (c) García Segura, Pol et al., 2023https://creativecommons.org/licenses/by/4.0/Expressió gènicaProteïnesCèl·lules immunocompetentsGene expressionProteinsImmunocompetent cellsinfo:eu-repo/semantics/article7300232025-04-28info:eu-repo/semantics/openAccess36715132