Isidro Llobet, AlbertJust Baringo, XavierEwenson, ArielÁlvarez Domingo, MercedesAlbericio Palomera, Fernando2013-12-202013-12-2020070006-3525https://hdl.handle.net/2445/48634A double side-reaction, consisting in the formation of Fmoc--Ala-OH and Fmoc--Ala-AA-OH, during the preparation of Fmoc protected amino acids (Fmoc-AA-OH) with Fmoc-OSu is discussed. Furthermore, the new Fmoc-2-MBT reagent is proposed for avoiding these side-reactions as well as the formation of the Fmoc-dipeptides (Fmoc-AA-AA-OH) and even tripeptides, which is another important side-reaction when chloroformates such as Fmoc-Cl is used for the protection of the -amino function of the amino acids.5 p.application/pdfeng(c) Wiley, 2007Reaccions químiquesSíntesi de pèptidsChemical reactionsPeptide synthesisinfo:eu-repo/semantics/article5491002013-12-20info:eu-repo/semantics/openAccess