Jané Salas, EnricLópez López, José, 1958-Roselló Llabrés, XavierRodríguez-Argueta, Oscar-FranciscoChimenos Küstner, Eduardo2013-07-092013-07-092012-01-011698-4447https://hdl.handle.net/2445/44663Podeu consultar la versió en castellà a http://hdl.handle.net/2445/135800The use of implants for oral rehabilitation of edentulous spaces has recently been on the increase, which has also led to an increase in complications such as peri-implant inflammation or peri-implantitis. Chronic inflammation is a risk factor for developing oral squamous cell carcinoma (OSCC). Objectives: To review the literature of cases that associate implant placement with the development of oral cancer. Study design: We present two clinical cases and a systematic review of literature published on the relationship between oral cancer and implants. Results: We found 13 articles published between the years 1996 and 2009, referencing 18 cases in which the osseointegrated implants are associated with oral squamous cell carcinoma. Of those, 6 articles were excluded because they did not meet the inclusion criteria. Of the 18 cases reported, only 7 cases did not present a previous history of oral cancer or cancer in other parts of the body. Conclusions: Based on the review of these cases, a clear cause-effect relationship cannot be established, although it can be deduced that there is a possibility that implant treatment may constitute an irritant and/or inflammatory cofactor which contributes to the formation and/or development of OSCC.6 p.application/pdfeng(c) Medicina Oral SL, 2012Implants dentalsCàncerMalalties de la bocaDental implantsCancerMouth diseasesinfo:eu-repo/semantics/article6017842013-07-09info:eu-repo/semantics/openAccess21743414