Bivins, AaronNorth, DevinAhmad, ArslanAhmed, WarishAlm, EricBeen, FredericBhattacharya, ProsunBijlsma, LubertusBoehm, Alexandria B.Brown, JoeButtiglieri, GianluigiCalabro, VincenzaCarducci, AnnalauraCastiglioni, SaraCetecioglu Gurol, ZeynepChakraborty, SudipCosta, FedericoCurcio, StefanoReyes, Francis L. de losDelgado Vela, JesethFarkas, KataFernández Cassi, XavierGerba, CharlesGerrity, DanielGironès Llop, RosinaGonzález, RaulHaramoto, EijiHarris, AngelaHolden, Patricia A.Islam, Md. TahmidulJones, Davey L.Kasprzyk-Hordern, BarbaraKitajima, MasaakiKotlarz, NadineKumar, ManishKuroda, KeisukeLa Rosa, GiuseppeMalpei, FrancescaMautus, MarianaMcLellan, Sandra L.Medema, GertjanMeschke, John ScottMueller, JochenNewton, Ryan J.Nilsson, DavidNoble, Rachel T.Nuijs, Alexander vanPeccia, JordanPerkins, T. AlexPickering, Amy J.Rose, Joan B.Sánchez, GloriaSmith, AdamStadler, LaurenStauber, ChristineThomas, KevinVoorn, Tom van derWigginton, KristaZhu, KevinBibby, Kyle2024-10-312024-10-312020-07-070013-936Xhttps://hdl.handle.net/2445/216164Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel member of the Coronaviridae family, has been identified as the etiologic agent of an ongoing pandemic of severe pneumonia known as COVID-19. To date there have been millions of cases of COVID-19 diagnosed in 184 countries with case fatality rates ranging from 1.8% in Germany to 12.5% in Italy. Limited diagnostic testing capacity and asymptomatic and oligosymptomatic infections result in significant uncertainty in the estimated extent of SARS-CoV-2 infection. Recent reports have documented that infection with SARS-CoV-2 is accompanied by persistent shedding of virus RNA in feces in 27% to 89% of patients at densities from 0.8 to 7.5 log10 gene copies per gram. The presence of SARS-CoV-2 RNA in feces raises the potential to survey sewage for virus RNA to inform epidemiological monitoring of COVID-19, which we refer to as wastewater-based epidemiology (WBE), but is also known as environmental surveillance.4 p.application/pdfeng(c) American Chemical Society, 2020COVID-19SARS-CoV-2Aigües residualsEpidemiologiaCOVID-19SARS-CoV-2SewageEpidemiologyinfo:eu-repo/semantics/article7103262024-10-31info:eu-repo/semantics/openAccess