Garcia, Juan IgnacioMambuque, EdsonNguenha, DinisVilanculo, FaustinoSacoor, CharfudinSequera Buzarquis, Victor GuillermoFernández Quevedo, ManuelLerroux-La Pierre, MaximeChiconela, HelioFaife, Luis A.Respeito, DurbalSaavedra, BelénNhampossa, TaciltaLópez Varela, ElisaGarcía-Basteiro, Alberto L.2022-03-012022-03-0120202045-2322https://hdl.handle.net/2445/183610Tuberculosis (TB) misdiagnosis remains a public health concern, especially among people living with HIV (PLHIV), given the high mortality associated with missed TB diagnoses. The main objective of this study was to describe the\xC2\xA0all-cause mortality, TB incidence rates and their\xC2\xA0associated risk factors in a cohort of PLHIV with presumptive TB in whom TB was initially ruled out. We retrospectively followed a cohort of PLHIV with presumptive TB over a 2\xC2\xA0year-period in a rural district in Southern Mozambique. During the study period 382 PLHIV were followed-up. Mortality rate was 6.8/100 person-years (PYs) (95% CI 5.2-9.2) and TB incidence rate was 5.4/100 PYs (95% CI 3.9-7.5). Thirty-six percent of deaths and 43% of TB incident cases occurred in the first 12\xC2\xA0months of the follow up. Mortality and TB incidence rates in the 2-year period after TB was initially ruled out was very high. The\xC2\xA0TB diagnostic work-up and linkage to HIV\xC2\xA0care should be strengthened to decrease TB burden and all-cause mortality among PLHIV with presumptive TB.11 p.application/pdfengcc by (c) Garcia, Juan Ignacio et al, 2020http://creativecommons.org/licenses/by/3.0/es/Persones seropositivesTuberculosiHIV-positive personsTuberculosisinfo:eu-repo/semantics/article2022-02-25info:eu-repo/semantics/openAccess32963296