Rodríguez Cabrera, Hortensia MaríaMartin, OsnieskiSuárez, MargaritaMartín, NazarioAlbericio Palomera, Fernando2020-03-112020-03-112011-11-211420-3049https://hdl.handle.net/2445/152588Here we describe the efficient synthesis of alkyl 4-arylsubstituted-6-chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylates and 4-arylsubstituted-4,7-dihydro-furo[3,4-b]pyridine-2,5(1H,3H)-diones via microwave-accelerated reaction of alkyl 4-arylsubstituted-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylates with the appropriate reagents. This eco-friendly approach to these valuable dihydropyridine derivatives does not involve the harsh or highly contaminating conditions common in classical heating and offers a reduction or even elimination of solvent use and recovery, simplification of the work-up procedures, facility of scale up, and low energy consumption, in addition to moderate to higher yields.16 p.application/pdfengcc-by (c) Rodríguez, Hortensia et al., 2011http://creativecommons.org/licenses/by/3.0/esEscalfament per microonesMolèculesQuímica verdaCalefaccióMicrowave heatingMoleculesGreen chemistryHeatinginfo:eu-repo/semantics/article6139342020-03-11info:eu-repo/semantics/openAccess22105712