Amat Tusón, MercedesKöver, AndreaJokic, DanicaLozano, OscarPérez Bosch, MariaLandoni, NicolaSubrizi, FabianaBautista, JesúsBosch Cartes, Joan2015-01-082015-01-0820101551-7012https://hdl.handle.net/2445/61086A straightforward synthesis of the Met antagonist JLK1360 involving an alkylationcyclocondensation process using aminothiazole 1 and nitrophenacyl bromide 2, reduction of the nitro group, and coupling of the resulting tetracyclic aniline 5 with an appropriate N-acyl alanine derivative, is reported.7 p.application/pdfengcc-by-nc (c) Amat Tusón, Mercedes et al., 2010http://creativecommons.org/licenses/by-nc/3.0/esBioquímicaAminesDianes farmacològiquesProteïnes quinasesTransducció de senyal cel·lularBiochemistryAminesDrug targetingProtein kinasesCellular signal transductioninfo:eu-repo/semantics/article5687392015-01-08info:eu-repo/semantics/openAccess