Soriano i Fradera, JordiLópez Poyatos, Ana2021-10-262021-10-262021-07https://hdl.handle.net/2445/180829Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2021, Tutor: Jordi Soriano FraderaWe studied the activity and functional network characteristics of neurons derived from human induced pluripotent stem cells (iPSCs) grown in culture. The cells were obtained from healthy and Parkinson’s–affected patients. Using a network perspective, different magnitudes were analyzed to demonstrate connectivity and activity differences between healthy controls, diseased Parkinson’s cultures, and genetically cured ones. We unveiled an excess of integration and a loss of both modularity and small–worldness for Parkinson’s diseased cultures. The study may help the medical society to better understand the disease and develop efficient therapies5 p.application/pdfengcc-by-nc-nd (c) López, 2021http://creativecommons.org/licenses/by-nc-nd/3.0/es/Xarxes neuronals (Neurobiologia)Cèl·lules mareMalaltia de ParkinsonTreballs de fi de grauNeural networks (Neurobiology)Stem cellsParkinson's diseaseBachelor's thesesinfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/openAccess