Pinyol, RoserSia, DanielaLlovet i Bayer, Josep Maria2020-01-082020-01-082019-01-071078-0432https://hdl.handle.net/2445/147198Next-generation sequencing has provided information on actionable targets and biomarkers of response in oncology. In hepatocellular carcinoma (HCC), Wnt/CTNNB1 mutations characterize the immune-excluded class (cold tumors) and might represent the biomarkers predicting resistance to immune checkpoint inhibitors. Large-scale validation of these data is needed to customize immunotherapy in advanced HCC.See related article by Harding et al.©2019 American Association for Cancer Research.4 p.application/pdfeng(c) American Association for Cancer Research, 2019Marcadors bioquímicsCàncer de fetgeBiochemical markersLiver cancerinfo:eu-repo/semantics/article7007522020-01-08info:eu-repo/semantics/openAccess421769930617138