Gómez Roig, Ma. DoloresMazarico Gallego, EdurneValladares, EstherGuirado, LauraFernandez-Arias, MireiaVela Martínez, Antonio2016-10-192016-10-192015-05-271932-6203https://hdl.handle.net/2445/102727Abstract OBJECTIVE: The objective of this study is to measure aortic intima-media thickness (aIMT) and aortic diameter (AD) in appropriate for gestational age (AGA) fetuses, small for gestational age (SGA) fetuses, and intrauterine growth restricted (IUGR) fetuses. METHODS: Case-control study performed between June 2011 and June 2012. Forty-nine AGA fetuses, 40 SGA fetuses, and 35 IUGR fetuses underwent concomitant measurement of aIMT and AD at a mean gestational age of 34.4 weeks. RESULTS: Median aIMT was higher in fetuses with IUGR (0.504 mm [95%CI: 0.477-0.530 mm]), than in SGA fetuses (0.466 mm [95% CI: 0.447-0.485 mm]), and AGA fetuses (0.471 mm [95% CI: 0.454-0.488 mm]) (p = 0.023). Mean AD was significantly lower in fetuses with IUGR (4.451 mm [95% CI: 4.258-4.655 mm]), than in AGA fetuses (4.74 mm [95% CI: 4.63-4.843 mm]) (p = 0.028). CONCLUSIONS: Growth restricted fetuses have a thicker aortic wall than AGA and SGA fetuses, which possibly represents preclinical atherosclerosis and a predisposition to later cardiovascular disease.9 p.application/pdfengcc-by (c) Gómez Roig, Ma. Dolores et al., 2015http://creativecommons.org/licenses/by/3.0/esFetusAortaMalalties cardiovascularsAntropometriaCreixement fetalAterosclerosiEstudi de casosFetusAortaCardiovascular diseasesAnthropometryFetal growthAtherosclerosisCase studiesinfo:eu-repo/semantics/article6544722016-10-19info:eu-repo/semantics/openAccess26017141