Mateu de Antonio, JavierBerlana, DavidPons Busom, MontserratBadia Tahull, Maria BellaMiana Mena, María TeresaMartínez Caste, BeatrizSunyer Esquerrà, NeusSanmartin Suñer, MónicaGonzález Valdivieso, JuanLeiva Badosa, ElisabetMartínez Bernabé, EvaMurgadella Sancho, AnnaMirerachs Aranda, NuriaVila Bundó, AnnaFernández Morató, JordiVitales Farrero, María Teresa2020-12-172020-12-172018-03-01https://hdl.handle.net/2445/172840Objective: this study assessed the incidence of hyperglycemia, hypertriglyceridemia, and liver function test (LFT) alterations among patients older and younger than 65 years receiving parenteral nutrition (PN). A secondary objective was to compare the incidence of any of these three events. Material and methods: inclusion criteria were non-critically ill adult inpatients receiving PN for 7 days in 15 hospitals in Spain. Exclusion criteria were hyperglycemia, hypertriglyceridemia, LFT alterations, sepsis, shock, pancreatic/hepatobiliary surgery, renal failure, diabetes mellitus (DM) type 1, insulin-treated DM type 2, acute DM complications, or obesity prior to PN. Patients were classified into groups YOUNG (aged 35-64) and OLD (aged 65-95). Results: this study recruited 200 patients. Group YOUNG included 63 (31.5%) patients and OLD, 137 (68.5%). Hyperglycemia appeared in 37 (18.5%) patients, eight (12.7%) in group YOUNG and 29 (21.2%) in group OLD (p = 0.174). Hypertriglyceridemia appeared in only one (0.7%) patient. LFT alterations appeared in 141 (70.5%) patients, 44 (69.8%) in group YOUNG and 97 (70.8%) in group OLD (p = 1.000). The model for hyperglycemia included DM type 2, previous surgical procedure, and use of hyperglycemia-inducing medications. The model for LFT alteration included previous surgical procedure, amount of lipids and amino acids, medications causing LFT alterations and a trend for age group. The model for any event included surgical procedure, DM type 2, and medications causing alterations. Conclusion: patients of 65 years receiving PN had similar incidences of hyperglycemia, hypertriglyceridemia, and LFT alterations as younger patients. Additionally, older patients had trends toward lower LET alterations.7 p.application/pdfengcc by-nc-sa (c) SENPE; Arán Ediciones S.L.http://creativecommons.org/licenses/by-nc-sa/3.0/es/HiperglucèmiaMalalties de les persones gransHyperglycemiaOlder people diseasesinfo:eu-repo/semantics/article2020-12-04info:eu-repo/semantics/openAccess