Narváez, JavierSánchez Fernández, Simón ÁngelSeoane Mato, DanielDíaz González, FedericoBustabad, Sagrario2020-11-042020-11-042020-06-30https://hdl.handle.net/2445/171791To estimate the prevalence of Sjogren's syndrome (SS) in the adult Spanish population we performed a population-based multicenter cross-sectional study. Cases were defined by the American-European Consensus Group criteria proposed in 2002. A total of 4,916 subjects aged 20 years or over were included. The estimated prevalence of SS (including primary and secondary forms) in the adult population in Spain was 0.33% (95% CI 0.21-0.53). Extrapolating to the total population of the country aged >= 20 years (around 37.7 million persons), there would be around 125,000 cases of SS in Spain. Considering only primary SS, the estimated prevalence was 0.25% (95% CI 0.15-0.43) or 1 person in 400. The prevalence of primary SS in Spain is comparable to that reported in other European studies with a similar design and diagnostic criteria. Based on these results, primary SS could not be considered a rare (orphan) disease. Only 50% of cases had already been diagnosed with SS prior EPISER 2016 study, confirming the existence of a non-negligible proportion of undiagnosed cases in the general population.10 p.application/pdfengcc by (c) Narváez et al., 2020http://creativecommons.org/licenses/by/3.0/es/Síndrome de SjögrenMalalties autoimmunitàriesSjogren's syndromeAutoimmune diseasesinfo:eu-repo/semantics/article2020-11-03info:eu-repo/semantics/openAccess32606345