Verdaguer i Espaulella, XavierSalomó i Prat, ErnestRojo Solé, Josep MariaFernández Sabaté, Marc2019-07-292021-06-202019-06https://hdl.handle.net/2445/138499Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2019, Tutors: Xavier Verdaguer Espaulella, Ernest Salomó i Prat, Josep Mª Rojo SoléIn this work, three acetophenone N-phenyl imine derivatives functionalized in the para position have been prepared and cyclometallated to Ir-MaxPHOX catalyst. One of the additives has a hydrogen bond acceptor group, while the others have bulky substituents. The behavior of these compounds in asymmetric hydrogenation of acetophenone N-methyl and N-phenyl imine substrates has been studied. The additive containing a hydrogen bond acceptor provided better enantioselectivity than the others. This reinforces the hypothesis that a hydrogen bond interaction between the catalyst and the substrate would increase the selectivity. Additives with bulky substituents provided worse results, probably due to steric hindrance, decreasing the selectivity44 p.application/pdfengcc-by-nc-nd (c) Fernández, 2019http://creativecommons.org/licenses/by-nc-nd/3.0/es/IridiHidrogenacióTreballs de fi de grauIridiumHydrogenationBachelor's thesesNovel cyclometallated iridium catalysts for asymmetric hydrogenation of N-methyl and N-phenyl iminesNous catalitzadors ciclometal·lats d’iridi per hidrogenacions asimètriques d’N-metil i N-fenil iminesinfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/openAccess