Amat Tusón, MercedesLlor Brunés, NúriaSubrizi, FabianaPérez Bosch, MariaMolins i Grau, EliesBosch Cartes, Joan2020-11-042020-11-0420131434-193Xhttps://hdl.handle.net/2445/171749Cyclization of the lactam carbonyl on the indole ring in tryptophanol-derived oxazolopiperidone lactams 2 and 6, under the classical POCl3-promoted Bischler-Napieralski conditions and under neutral conditions via the corresponding thiolactam, has been studied. Whereas tricyclic lactam 2 only leads to products coming from an α-amidoalkylation process, bicyclic lactam 6 undergoes cyclization on the lactam carbonyl, leading to the expected indolo[2,3-a]quinolizidine derivatives.7 p.application/pdfeng(c) Wiley-VCH, 2013LactamesTriptòfanCompostos heterocíclicsSíntesi orgànicaLactamsTryptophanHeterocyclic compoundsOrganic synthesisinfo:eu-repo/semantics/article6205782020-11-04info:eu-repo/semantics/openAccess