Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles]

Pérez Bosch, MariaRamos, CarlosMassi, LuciaGazzola, SilviaTaglienti, ChiaraYayik, NihanMolins i Grau, EliesViayna Gaza, AntonioLuque Garriga, F. XavierBosch Cartes, JoanAmat Tusón, Mercedes2020-07-032020-07-032017-08-041523-7060https://hdl.handle.net/2445/167518A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported.4 p.application/pdfeng(c) American Chemical Society , 2017Síntesi orgànicaEnantiòmersOxidacióCompostos heterocíclicsOrganic synthesisEnantiomersOxidationHeterocyclic compoundsEnantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles]info:eu-repo/semantics/article6776972020-07-03info:eu-repo/semantics/openAccess